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Ингибиторы ангиотензинпревращающего фермента при инфаркте миокарда: итоги исследовательского проекта SMILE

 

magazine-vrach-2012-07-003

Ингибиторы ангиотензинпревращающего фермента при инфаркте миокарда: итоги исследовательского проекта SMILE

Многолетний научный проект SMILE с использованием зофеноприла продемонстрировал целесообразность и безопасность раннего назначения препарата у гемодинамически стабильных больных с передним инфарктом миокарда без тромболитической терапии, а также представил свидетельства клинического значения особенностей отдельных ингибиторов ангиотензинпревращающего фермента, связанных с их химикофармакологическими свойствами.
Angiotensin-converting enzyme inhibitors in myocardial infarction: results of the smile study project
The long-term SMILE study project using zofenopril has demonstrated that it is expedient and safe to early use the drug in hemodynamically stable patients with anterior myocardial infarction receiving no thrombolytic therapy and provided evidence that the specific features of individual angiotensin-converting enzyme inhibitors, which are associated with their chemicopharmacological properties, are of clinical value.
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